Michelle Lou composes mainly in the realm of electro-acoustic music, both in hardware and in computer based forms. She has also created large scale sound installations which are often performative and collaborative. She performs and improvises on acoustic and electric bass, electric guitar, and on laptop and various electronics. Her work has been presented at Wien Modern, Donaueschinger Musiktage, Darmstadt Ferienkurse, Bludenzer Tage zeitgemäßer Musik, The Festival of New American Music (Sacramento), the MATA Festival (New York City), The 66th American Music Festival at the National Gallery in Washington D.C., The Rainy Days Festival (Luxembourg), Ultima Festival (Oslo), Chance and Circumstance (Brooklyn), Klub Katarakt (Hamburg), Klangwerkstatt and MaerzMusik (both in Berlin), amongst others.